Adult Onset Langerhans’ Cell Histiocytosis
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Case Report

Adult Onset Langerhans’ Cell Histiocytosis

Turk J Dermatol 2014;8(4):236-239 DOI: 10.4274/tdd.1776
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Abstract

Langerhans’ cell histiocytosis (LCH) is a group of diseases of unknown cause resulting from abnormal proliferation of bone marrow-originated dendritic cells called histiocytes. The incidence is between 0.5-5.4 per million. More common in childhood, it is extremely rare in adults. In adults, pulmonary involvement with Langerhans’ cell histiocytosis usually occurs as a single-system disease. In this article, the clinical, radiological and histopathological findings of a 51-year-old male patient with both skin, bone and pulmonary involvement were presented and discussed with recent literature.

Keywords: Langerhans’ cell histiocytosis, adult onset, lung involvement, skin, bone, chemotherapy