ABSTRACT
A limited number of cases have been reported showing the togetherness of mycosis fungoides (MF) and pityriasis lichenoides (PL) which are two rare diseases. As we observed PL et varioliformis acuta development soon after MF in a pediatric patient, were reviewed the related cases in the literature and determined that relationship could be in four different possible ways: the clinical presentation of MF with PL-like lesions, coexistence of MF and PL lesions, PL’s pioneering role in MF and as observed in our case, the occurrence of PL in a patient followed-up with a diagnosis of MF. Considering this wide spectrum of the relationship between two diseases, their pathogenesis may be partly associated.
References
1Furlan FC, Sanches JA. Hypopigmented mycosis fungoides: a review of its clinical features and pathophysiology. An Bras Dermatol 2013;88:954-60.
2Heng YK, Koh MJA, Giam YC, et al. Pediatric mycosis fungoides in Singapore: a series of 46 children. Pediatr Dermatol 2014;31:477-82.
3Lam J, Pope E. Pediatric pityriasis lichenoides and cutaneous T-cell lymphoma. Curr Opin Pediatr 2007;19:441-5.
4Ko JW, Seong, JY, Suh KS, et al. Pityriasis lichenoides‐like mycosis fungoides in children. Br J Dermatol 2000;142:347-52.
5Kavala M, Zindanci I, Sudogan S, et al. Pityriasis lichenoides-like mycosis fungoides. a case report. Eur J Pediat Dermatol 2010;20:231-4.
6de Unamuno Bustos B, Ferriols AP, Sánchez RB, et al. Adult pityriasis lichenoides-like mycosis fungoides: a clinical variant of mycosis fungoides. Int J Dermatol 2014;53:1331-8.
7Fortson JS, Schroeter AL, Esterly NB. Cutaneous T-cell lymphoma (parapsoriasis en plaque). An association with pityriasis lichenoides et varioliformis acuta in young children. Arch Dermatol 1990;126:1449-53.
8Thomson KF, Whittaker SJ, Russel-Jones R, et al. Childhood cutaneous T-cell lymphoma in association with pityriasis lichenoides chronica. Br J Dermatol 1999;141:1146-8.
9Tomasini D, Zampatti C, Palmedo G, et al. Cytotoxic mycosis fungoides evolving from pityriasis lichenoides chronica in a seventeen-year-old girl. Report of a case. Dermatology 2002;205:176-9.
10Boccara O, Blanche S, de Prost Y, et al. Cutaneous hematologic disorders in children. Pediatr Blood Cancer 2012;58:226-32.
11Pileri A, Neri I, Raone B, et al. Mycosis fungoides following pityriasis lichenoides: an exceptional event or a potential evolution? Pediatr Blood Cancer 2012;58:306.
12Magro CM, Crowson AN, Morrison C, et al. Pityriasis lichenoides chronica: stratification by molecular and phenotypic profile. Hum Pathol 2007;38:479-90.
13Ersoy-Evans S, Greco MF, Mancini AJ, et al. Pityriasis lichenoides in childhood: a retrospective review of 124 patients. J Am Acad Dermatol 2007;56:205-10.
14Kempf W, Kutzner H, Kettelhack N, et al. Paraneoplastic pityriasis lichenoides in cutaneous lymphoma: a case report and review of the literature on paraneoplastic reactions of the skin in lymphoma and leukaemia. Br J Dermatol 2005;152:1327-31.
