Evaluation of Treatment Response by Using a Handheld Dermoscope in Patients with Alopecia Areata
PDF
Cite
Share
Request
Original Investigation
P: 143-148
September 2018

Evaluation of Treatment Response by Using a Handheld Dermoscope in Patients with Alopecia Areata

Turk J Dermatol 2018;12(3):143-148
1. Özel Dr. Ayşegül Saltat Polikliniği, Dermatoloji Kliniği, İstanbul, Türkiye
2. Başkent Üniversitesi Tıp Fakültesi, Dermatoloji Anabilim Dalı, Ankara, Türkiye
No information available.
No information available
Received Date: 18.02.2018
Accepted Date: 08.06.2018
Publish Date: 31.08.2018
PDF
Cite
Share
Request

ABSTRACT

Objective:

Treatment response is variable in patients with alopecia areata, and may not be understood until significant hair growth is obtained. The aim of this study is to determine the potential benefit of handheld dermoscope in evaluating of treatment success in alopecia areata.

Methods:

Forty-nine patients who were diagnosed with alopecia areata were included in the study. Diagnosis was established clinically, and scalp biopsy was performed in doubtful cases. Dermoscopic examinations were performed by a polarized light and handheld dermoscope with 10-fold magnification. The images were taken by a digital camera with threefold optical zoom. Among 49 patients, 30 of them were followed-up during six months and concluded the study.

Results:

Of the 30 patients, 12 had a complete response to treatment (group 1), whereas 18 patients did not respond well to treatment or were remained completely responseless (group 2). When the trichoscopic findings were examined pretreatment, only thinning hairs were significantly more frequent in group 1 than group 2. The pre- and posttreatment findings of group 1 was shown that yellow dots, black dots, thinning hairs and broken hairs decreased or disappeared after the treatment, and this difference was statistically significant. In all of the patients in the first group, short terminal hairs were appeared at the end of treatment.

Conclusion:

According to our study, polarized light handheld dermoscope provides benefit for the evaluation of treatment success in patients with alopecia areata.

References

1 Alkhalifah A, Alsantali A, Wang E et al. Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis. J Am Acad Dermatol 2010;62:177-88.
2 El Taieb MA, Ibrahim H, Nada EA, et al. Platelets rich plasma versus minoxidil 5% in treatment of alopecia areata: A trichoscopic evaluation. Dermatol Ther 2017;30:1-6.
3 Ganjoo S, Thappa DM. Dermoscopic evaluation of therapeutic response to an intralesional corticosteroid in the treatment of alopecia areata. Indian J Dermatol Venereol Leprol 2013;79:408-17.
4 Inui S, Nakajima T, Itami S. Dry dermoscopy in clinical treatment of alopecia areata. J Dermatol 2007;34:635-9.
5 Inui S, Nakajima T, Nakagawa K, et al. Clinical significance of dermoscopy in alopecia areata: analysis of 300 cases. Int J Dermatol 2008;47:688-93.
6 Seo J, Lee JW, Choi MJ et al. Serial trichoscopy vs. modified hair pull test for monitoring the disease activity and treatment response of localized alopecia areata. J Eur Acad Dermatol Venereol 2017;31:e149-e50.
7 Olsen E, Hordinsky M, McDonald-Hull S, et al. Alopecia areata investigational assessment guidelines. National Alopecia Areata Foundation. J Am Acad Dermatol 1999;40:242-6.
8 Tosti A, Piraccini BM, Pazzaglia M, et al. Clobetasol propionate 0.05% under occlusion in the treatment of alopecia totalis/universalis. J Am Acad Dermatol 2003;49:96-8.
9 MacDonald Hull SP, Wood ML, Hutchinson PE et al. Guidelines for the management of alopecia areata. Br J Dermatol 2003;149:692-9.
10 Ross EK, Vincenzi C, Tosti A. Videodermoscopy in the evaluation of hair and scalp disorders. J Am Acad Dermatol 2006;55:799-806.
11 Karadağ Köse Ö, Güleç AT. Clinical evaluation of alopecias using a handheld dermatoscope. J Am Acad Dermatol 2012;67:206-14.
12 Kibar M, Aktan Ş, Lebe B, et al. Trichoscopic findings in alopecia areata and their relation to disease activity, severity and clinical subtype in Turkish patients. Australas J Dermatol 2015;56:e1-e6.
13Lacarrubba F, D’Amico V, Nasca MR, et al. Use of dermatoscopy and videodermatoscopy in therapeutic follow-up: a review. Int J Dermatol 2010;49:866-73.
Article is only available in PDF format. Show PDF
2024 ©️ Galenos Publishing House