ABSTRACT

Leiomyomatosis cutis is a rare disease characterized by oval shaped, red-brown follicular groups of papulonodular lesions especially located on the lower limbs, in which the lesions originate from smooth muscle cells.

A fifty-three-year-old female patient was admitted to our clinic with multiple painful nodules on the body. An ischemic stroke, total hysterectomy for leiomyoma, oopherectomy, nephrolitiasis and renal cysts were present in her past medical history. Dermatologic examination revealed multiple, painful, red-brown nodules forming clusters on the left scapular area, bilateral gluteal area and lower limbs. Histopathological examination of the lesional biopsy diagnosed as leiomyoma. Treatment started with gabapentin, paracetamol, tramadol hydrochloride and, amitriptyline, which produced relief of the pain at the end of three weeks. To the best of our knowledge, this is the first case report in our country. (Turk J Dermatol 2011; 5: 101-3)