ABSTRACT

This study was performed to determine the morphological pattern of MF among Saudi patients at King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

The analysis included 151 skin cancers with a histological diagnosis among Saudi patients between Jan 1995 and Dec 2012. Morphological pattern of MF by age, sex , anatomic location, histological and immunohistochemical features was examined.

MF accounted for 12.5%of all histologically diagnosed cases of skin cancer among Saudi patients.It ranked as the third skin cancer in the order of frequency with a mean age of 44.6 years and male predominance. The most frequent sites of distribution were the thighs followed by legs and the most frequent histological type was the early or patch type. The atypical lymphocytes showed CD 3 expression in all cases with immunohistochemical studies.CD4 was positive in 26.6% while all cases were negative for CD 20.

In conclusion, MF is a rare tumor and ranked third in frequency of skin cancers among Saudis showing predilection for younger males which highlights the ethnic and/or regional variation in the clinico-epidemiological characteristics of MF