Pemphigus is a bullous auto-immune disease which has high mortality and morbidity rates and affects the skin and mucosa. Corticosteroids are still the baseline treatment modality of pemphigus management. However, non-steroidal drugs and methods have been used more frequently in patients with pemphigus who are non-responders to conventional therapy or have severe side effects. In this article we aimed to review unconventional therapy modalities in patients with pemphigus.

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