ABSTRACT
Pustular psoriasis is a rare variant of psoriasis characterized by recurrent pustule formation on the erythematous base. Pustular exacerbation in plaque psoriasis can be triggered by systemic steroid use and its abrupt cessation, drugs such as salicylate, iodine, lithium, hydroxychloroquine, interferon-alpha, infections, pregnancy, and hypocalcemia. As far as is known, the pustular exacerbation in plaque psoriasis after hepatitis B vaccination has not been previously defined in the literature, and this is the first case report as a new trigger agent.
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